Open Source Bioprinter

Overview

The 'Nydus One Bioprinter' is an extrusion-based Bioprinter. It operates via a controllable mechanical press, to extrud cell-laden bioinks. Basis for the Bioprinter is a remixed version of the RepRap Prusa i3 MK2-X. The printer is capable of printing all three common cell sources: cell-lines, primary tissue and stem cells. To operate the Bioprinter, Dennis Ogiermann has written a "Composer". This open source pathplanning tool allows to dispense into standarized container and allows repetitive experiment designs. The 'Nydus One Bioprinter' was established using a experimental 'Microgel Approach'. Main idea of the approach is the use of a thermoreversible gelatin bath (called Slurry Bath) to print objects with complex geometry. The approach was published by Hinton et al. in 2015 (see Sources).

Development

To track and coordinate our development efforts we use an OpenProject repository: See OpenProject Homescreen

OSF Repository

To allow sharing the required soft- and hardware, we have created an OSF repository: Open Science Framework Bioprinter Project

Costs

In summary: XXX

Detailed List

Sources

Basis

Frame Modifications

Assembly Guide

Extruder Parts

Microgel Approach